We have put in multiple tickets regarding our issue since Sunday with no results
You didn't mention any ticket number nor who you are, but assuming you're the same Steve who opened 4 tickets today containing comments similar to the above, you should know that the last ticket we have from you (prior to today) was submitted back on April 30th. If you tried opening others since Sunday we did not receive them -- to ensure delivery, make sure you're opening them via our web-based helpdesk interface and not via E-mail.
and as of yesterday at 12pm edt we can no long re issue our license we have had for 2 years now
That's because you have reissued it over and over for some reason, and are now at the reissuance limit for today.
does anyone no of a way to get hold of these people?
Yes, you can open a ticket. You seem to be insinuating that we don't respond, but your first ticket today was opened at 11:32AM Pacific, and it looks like Sam managed to reply to you at 11:33AM, so I think less-than-one-minute is a pretty good turnaround time.